Laboratório de Genômica Estrutural

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Laboratório de Genômica Estrutural

Av. Carlos Chagas Filho s/n, CCS, bloco C, sala C0-36
Rio de Janeiro
21941-900

Tel: 55-21-3938-6538
Fax: 55-21-2280-8193

LABGENEST > PUBLICAÇÕES

PUBLICAÇÕES

2014	FAUSTINO, A. F.; CARVALHO, F. A.; MARTINS, I. C.; MOHANA-BORGES, R.; CASTANHO, M. A. R. B.; ALMEIDA, F. C. L.; DA POIAN, A. T., SANTOS, N. C. Dengue Virus Capsid Protein Interacts Specifically with Very Low Density Lipoproteins. Nanomedicine, v.10, p. 247-255.

2013	FREIRE, J. M.; VEIGA, A. S.; CONCEIÇÃO, T. M.; KOWALCZYK, W.; MOHANA -BORGES, R. ; ANDREU, D.; SANTOS, N. C.; DA POIAN, A. T.; CASTANHO, M. A. R. B. Intracellular Nucleic Acid Delivery by the Supercharged Dengue Virus Capsid Protein. Plos One, v.8, p.e81450.

2013	DA COSTA, E. C. B.; AMORIM, R.; DA SILVA, F. C.; ROCHA, D. R.; PAPA, M. P.; DE ARRUDA, L. B.; MOHANA-BORGES, R.; FERREIRA, V. F.; TANURI, A.; DA COSTA, L. J.; FERREIRA, S. B. Synthetic 1,4-Pyran Naphthoquinones Are Potent Inhibitors of Dengue Virus Replication. Plos One, v.8, p.e82504.

2013	BELGRANO, F. S; DE ABREU DA SILVA, I. C.; BASTOS DE OLIVEIRA, F. M.; FANTAPPIÉ, M. R., MOHANA-BORGES, R. Role of the Acidic Tail of High Mobility Group Protein B1 (HMGB1) in Protein Stability and DNA Bending. Plos One., v.8, p.e79572.

2013	ALLONSO, D.; VAZQUEZ, S.; GUZMAN, M. G.; MOHANA-BORGES, R. High Mobility Group Box 1 Protein as an Auxiliary Biomarker for Dengue Diagnosis. The American Journal of Tropical Medicine and Hygiene, v. 88, p. 506-509.

2013	SILVA, E. M.; CONDE, J. N.; ALLONSO, D.; NOGUEIRA, M. L.; MOHANA-BORGES, R. Mapping the Interactions of Dengue Virus NS1 Protein with Human Liver Proteins Using a Yeast Two-Hybrid System: Identification of C1q as an Interacting Partner. Plos One, v. 8, p. e57514.

2012

CARVALHO, F. A.; CARNEIRO, F. A.; MARTINS, I. C.; ASSUNCAO-MIRANDA, I.; FAUSTINO, A. F.; PEREIRA, R. M.; BOZZA, P. T.; CASTANHO, M. A. R. B.; MOHANA-BORGES, R.; DA POIAN, A. T.; SANTOS, N. C. Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins. Journal of Virology (Print), v. 86, p. 2096-2108.

2012

BARROS, T. G.; ZORZANELLI, B. C.; PINHEIRO, S.; BRITO, M. A.; TANURI, A.; COSTA, E. C. B.; MOHANA-BORGES, R.; RODRIGUES, C. R.; SOUZA, A. T. M.; FERREIRA, V. F.; MURI, E. M. F. Novel peptide mimetics based on N-protected amino acids derived from isomannide as potential inhibitors of NS3 serine protease of Hepatitis C virus. Letters in Organic Chemistry, v. 9, p. 239-249.

2012

MARTINS, I.; GOMES NETO, F.; FAUSTINO, A.; CARVALHO, F.; CARNEIRO, F. A.; Bozza, P. T.; MOHANA-BORGES, R.; CASTANHO, M. A. R. B.; ALMEIDA, F. C.; Santos, N. C.; DA POIAN, A. T. The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif. Biochemical Journal (London. 1984), v. 444, p. 405-415,

2012

ALLONSO, D.; BELGRANO, F. S.; CALZADA, N.; GUZMÁN, M. G.; VÁZQUEZ, S.; MOHANA-BORGES, R. Elevated serum levels of high mobility group box 1 (HMGB1) protein in dengue-infected patients are associated with disease symptoms and secondary infection. Journal of Clinical Virology, v. 55, p. 214-219.

2012

RIBEIRO, F. S.; DE ABREU DA SILVA, I. C.; CARNEIRO, V. C.; BELGRANO, F. S.; MOHANA-BORGES, R.; DE ANDRADE ROSA, I.; BENCHIMOL, M.; SOUZA, N. R. Q.; MESQUITA, R. D.; SORGINE, M. H. F.; GAZOS-LOPES, F.; VICENTINO, A. R. R.; WU, W.; DE MORAES MACIEL, R.; DA SILVA-NETO, M. A. C.; FANTAPPIÉ, M. R. The Dengue Vector Aedes aegypti Contains a Functional High Mobility Group Box 1 (HMGB1) Protein with a Unique Regulatory C-Terminus. Plos One, v. 7, p. e40192.

2011

ALLONSO, D.; ROSA, M. S.; COELHO, D. R.; COSTA, S. M.; NOGUEIRA, R. M.; BOZZA, F. A.; DOS SANTOS, F. B.; ALVEZ, A. M. B.; MOHANA-BORGES, R. Polyclonal antibodies against properly folded Dengue virus NS1 protein expressed in E. coli enable sensitive and early dengue diagnosis. Journal of Virological Methods, V. 175, p. 109-116.

2011

AMDRADE, I. S.; VIANEZ, J. L.; GOULART, C. L.; HOMBLE, F.; RUYSSCHAERT, J. M.; VON KRUGER, W. M. A.; BISCH, P. M.; De SOUZA, W.; MOHANA-BORGES, R.; MOTTA, M. C. M. Characterization of a porin channel in the endosymbiont of the trypanosomatid protozoan Crithidia deanei. Microbiology (Reading. Print), V. 157, p. 2818-2830.

2011	COSTA, S. M.; YORIO, A. P.; GONCALVES, A. S.; VIDALE, M. M.; COSTA, E. C. B.; MOHANA-BORGES, R.; MOTTA, M. A.; FREIRE, M. S.; ALVES, A. M. B. Induction of a Protective Response in Mice by the Dengue Virus NS3 Protein Using DNA Vaccines. Plos One, v. 6, p. e25685.

2009

MELO, M. N.; SOUSA, F. J. R.; CARNEIRO, F. A.; CASTANHO, M. A. R. B.; VALENTE, A. P.; ALMEIDA, F.; DA POIAN, A. T.; MOHANA-BORGES, R. Interaction of the dengue virus fusion peptide with membranes by NMR: the essential role of the envelope protein Trp101 for membrane fusion. Journal of Molecular Biology, v. 392, p. 736-746.

2009

DIAZ, A.; FONTANA, E. C.; TODESCHINI, A. R.; SOULE, S.; GONZALEZ, H.; CASARAVILLA, C.; PORTELA, M.; MOHANA-BORGES, R.; MENDONÇA-PREVIATO, L.; PREVIATO, J. O.; FERREIRA, F. The Major Surface Carbohydrates of the ECHINOCOCCUS GRANULOSUS Cyst: Mucin-Type O-Glycans Decorated by Novel Galactose-Based Structures . Biochemistry (Easton), v. 48, p. 11678-11691.

2008

STAUFFER, F. J.; MELO, M. N.; CARNEIRO, F. A.; SOUZA, F. J. R.; JULIANO, M. A.; JULIANO, L.; MOHANA-BORGES, R.; Da POIAN, A. T. ; CASTANHO, M. A. R. B. . Interaction between dengue virus fusion peptide and lipid bilayers depends on peptide clustering. Molecular Membrane Biology, v. 25, p. 128-138.

2008	SIMON, S. M.; SOUSA, F. J. R.; MOHANA-BORGES, R.; WALKER, G. C. Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products. PNAS. Proceedings of the National Academy of Sciences of the United States of America, v. 105, p. 1152-1157.

2008	PORTUGAL, M. I.; TODESCHINI, A. R.; LIMA, C. S.; LIMA, C. A.; MOHANA-BORGES, R.; OTTENHOFF, T. H. M.; PREVIATTO, L. M.; PREVIATO, J. O.; PESSOLANI, M. C. V. Characterization of two heparan sulphate-binding sites in the mycobacterial adhesin Hlp. BMC Microbiology (Online), v. 8, p. 75.

2007	GUTIERREZ, A. L.; FARAGE, L.; MELO, M. N.; MOHANA-BORGES, R.; GUERARDEL, Y.; CODDEVILLE, B.; WIERUSZESKI, J.; PREVIATTO, L. M.; PREVIATO, J.O. Characterization of glycoinositolphosphoryl ceramide structure mutant strains of Cryptococcus neoformans. Glycobiology (Oxford), v. 17, p. 1C-11C.

2007	SCHWARZINGER, S.; MOHANA-BORGES, R.; Kroon, G. J. A.; DYSON, H. J.; WRIGHT, P. E. Structural characterization of partially folded intermediates of apomyoglobin H64F. Protein Science, v. 17, p. 313-321.

2006

SOUSA, F. J. R.; LIMA, L. M.; OLIVEIRA, C. L.; TORRIANI,I.; ALMEIDA, D. F.; FOGUEL, D.; SILVA, J. L.; MOHANA-BORGES, R. Tetramerization of the LexA Repressor in Solution: Implications for Gene Regulation of the E.coli SOS System at Acidic pH. Journal of Molecular Biology, v. 359, n.4, p. 1059-1074.

2006	FABER-BARATA, J.; MOHANA-BORGES, R.; LIMA, L. M. Specificity in DNA recogniFAtion by a peptide from papillomavirus E2 protein. FEBS Letters, v. 580, p. 1919-1924.

2006	DE ANDRADE ROSA, I.; EINICKER-LAMAS, M.; BERNARDO, R. R.; PREVIATTO, L. M.; MOHANA-BORGES, R.; MORGADO-DIAS, J. A.; BENCHIMOL, M. Cardiolipin in Hydrogenosomes: Evidence of Symbiotic Origin. Eukaryotic Cell, EUA, v. 5, p. 784-787.

2004	MOHANA-BORGES, R.; GOTO, N. K.; KROON, G. J. A.; DYSON, H. J.; WRIGHT, P. E. Structural Characterization of Unfolded States of Apomyoglobin using Residual Dipolar Couplings. Journal of Molecular Biology, v. 340, p. 1131-1142.

2002

SILVA, J. L.; OLIVEIRA, A. C.; GOMES, A. M. O.; LIMA, L. M.; MOHANA-BORGES, R.; PACHECO, A. B. F.; FOGUEL, D. Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly. Biochimica et Biophysica Acta. Protein Structure and Molecular Enzymology (Cessou em 2002. Cont. ISSN 1570-9639 Biochimica et Biophysica Acta. Protein, EUA, v. 1595, n.1-2, p. 250-265.

2000	OLIVEIRA,A. C.; GOMES,A.M.O.; ALMEIDA, F.; MOHANA-BORGES, R.; VALENTE, A. P.; REDDY, V. S.; JONHSON, J. E.; SILVA,J.L. Virus Maturation Targets the Capsid to Concerted Disassembly and Unfolding. The Journal of Biological Chemistry, EUA, v. 275, p. 16037-16043.

2000	MOHANA-BORGES, R.; PACHECO, A. B. F.; SOUZA, F. J. R.; FOGUEL,D.; ALMEIDA, D. F.; SILVA, J. L. LexA Repressor Forms Stable Dimers in Solution: The Role of Specific DNA in Targeting Protein-Protein Interactions. The Journal of Biological Chemistry (Print), EUA, v. 275, p. 4708-4712.

1999	MOHANA-BORGES, R.; SILVA, J. L.; SANZ, J. R.; GAY, G. P. Folding of a Pressure-Denatured Model Protein. PNAS. Proceedings of the National Academy of Sciences of the United States of America, EUA, v. 96, p. 7888-7893.

1999	MOHANA-BORGES, R.; SILVA, J. L.; GAY, G. P. Protein Folding in the Absence of Chemical Denaturants. Reversible Pressure Denaturation of the Noncovalent Complex Formed by the Association of Two Protein Fragments. The Journal of Biological Chemistry, EUA, v. 274, p. 7732-7740.